Colorado faces West Virginia in Week 11 of the 2025 college football season with West Virginia favored by 6.5 points and a total of 52.5 points scored. Colorado, under head coach Deion Sanders, has struggled recently, allowing at least 50 points in two consecutive games and failing to qualify for a bowl game. The team has made a quarterback change, starting true freshman Julian Lewis, a highly-rated recruit, hoping to boost their offense. Colorado's key receiver Omarion Miller has 28 catches for 521 yards and six touchdowns. West Virginia, led by coach Rich Rodriguez, has shown improvement, winning their last game as a 12.5-point underdog and covering in two of their past four games. They feature a balanced ground game with seven players averaging at least 24 carries, and their quarterback Scotty Fox Jr. is making his fourth start. The betting odds favor West Virginia, with the Mountaineers considered more likely to cover, although Colorado has been competitive in some games despite recent blowout losses. The SportsLine projection model predicts a total of 53 points, favoring the under, and suggests West Virginia has a better chance to cover the spread. The game will be streamed on Fubo, and betting experts recommend considering the over/under and spread based on recent team performances. Overall, West Virginia's recent form and improved offense give them an edge, but Colorado's big-play potential and recent competitive efforts keep the game unpredictable.